A highly sensitive distributed feedback (DFB) dye laser sensor for high frame rate imaging refractometry without moving parts is presented. The laser sensor surface comprises areas of different grating periods. Imaging in two dimensions of space is enabled by analyzing laser light from all areas in parallel with an imaging spectrometer. Refractive index imaging of a 2 mm by 2 mm surface is demonstrated with a spatial resolution of 10 μm, a detection limit of 8 10-6 RIU, and a framerate of 12 Hz, limited by the CCD camera. Label-free imaging of dissolution dynamics is demonstrated.
Anders Kristensen, Christoph Vannahme, Kristian T. Sørensen, and Martin Dufva, "Multi-wavelength laser sensor surface for high frame rate imaging refractometry
(Conference Presentation)," Proc. SPIE 9920, Active Photonic Materials VIII, 992023 (Presented at SPIE Nanoscience + Engineering: September 01, 2016; Published: 9 November 2016); https://doi.org/10.1117/12.2238109.5159519650001.
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