We demonstrate the long time trapping of single DNA molecules in liquids by feedback driven dynamic temperature fields. By spatially and temporally varying the temperature at a plasmonic nanostructure, thermophoretic drifts are induced that are used to trap single nano-objects. A feedback controlled switching of local temperature fields allows us to confine the motion of a single DNA molecule for minutes. The DNA conformation and conformation dynamics are analyzed in terms of a principle component analysis. Current results are in agreement with previous measurements in thermal equilibrium and suggest only a weak influence of the inhomogeneous temperature rise on the structure and dynamics in the trap.
Marco Braun, Tobias Thalheim, Katrin Günther, Michael Mertig, and Frank Cichos, "Thermophoretic trapping and manipulation of single molecules," Proc. SPIE 9922, Optical Trapping and Optical Micromanipulation XIII, 99220Z (Presented at SPIE Nanoscience + Engineering: August 30, 2016; Published: 23 November 2016); https://doi.org/10.1117/12.2239481.
Conference Presentations are recordings of oral presentations given at SPIE conferences and published as part of the conference proceedings. They include the speaker's narration along with a video recording of the presentation slides and animations. Many conference presentations also include full-text papers. Search and browse our growing collection of more than 12,000 conference presentations, including many plenary and keynote presentations.