From Event: SPIE Optical Engineering + Applications, 2016
Compared with other imaging probes such as fluorescent dyes and quantum dots, second-harmonic radiating imaging
probes (SHRIMPs) provide a unique ultrafast, coherent optical contrast that is free of photobleaching and emission
intermittency. Using the second-harmonic signal emitted from SHRIMPs, harmonic holography achieves threedimensional
holographic imaging with a color contrast similar to fluorescence microscopy where the uninterested
background scattering is efficiently suppressed by an optical filter. The coherent contrast provided by SHRIMPs also
enables imaging through turbid media via digital phase conjugation. Here we review the developments and applications
of SHRIMPs and harmonic holography.
Ye Pu and Demetri Psaltis, "Second-harmonic radiating imaging probes and harmonic holography," Proc. SPIE 9956, Ultrafast Nonlinear Imaging and Spectroscopy IV, 995608 (Presented at SPIE Optical Engineering + Applications: August 28, 2016; Published: 3 October 2016); https://doi.org/10.1117/12.2238511.
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