From Event: SPIE BiOS, 2023
High resolution optical imaging modalities such as optical coherence tomography and multiphoton microscopy have excellent specificity and sensitivity for early detection of cancer, however they may have very limited field of view. This small field of view makes visualizing the entirety of organs time-consuming or impractical. Wide field of view optical modalities such as narrowband or multispectral fluorescence imaging can be combined with high resolution imaging to identify suspicious areas for further investigation. Ovarian and gastric cancer both have poor prognosis unless they are detected early. We have utilized the dual field of view technique for examining the fallopian tubes and stomach, in order to create a viable screening method. Sub-mm to few-mm diameter endoscopes are configured with dual optical modalities, either combined in the same device or with a parent/babyscope design.
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Jennifer K. Barton, Andrew Rocha, Travis Sawyer, and Sarah Bohndiek, "Multiscale imaging for early cancer detection," Proc. SPIE PC12363, Multiscale Imaging and Spectroscopy IV, PC1236301 (Presented at SPIE BiOS: January 28, 2023; Published: 17 March 2023); https://doi.org/10.1117/12.2658810.6321584034112.