Focused ultrasound (FU) is an emerging non-invasive and non-ionizing therapeutic technology that has the potential to treat a variety of medical conditions. FU can heat up, destroy, or change target tissue while minimizing damage to tissue outside the target area by precisely focusing on ultrasonic beams. Understanding and characterizing high-intensity FU is essential for planning and administering therapeutic procedures safely. Modeling nonlinear ultrasound is a computationally demanding problem. The complex diffraction structure requires the use of accurate diffraction models and a fine spatial numerical grid. In this work, we will propose an accelerated and more efficient strategy in which the nonlinearity in the simulation is monitored, and a corresponding increase in the resolution required to resolve higher harmonics is actively implemented.

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Ahmed Sallam and Shima Shahab, "Accelerated high-intensity ultrasound simulations," Proc. SPIE PC12483, Active and Passive Smart Structures and Integrated Systems XVII, PC124830E (Presented at SPIE Smart Structures + Nondestructive Evaluation: March 15, 2023; Published: 28 April 2023); https://doi.org/10.1117/12.2658737.6323738644112.