Atmospheric spectroscopists have for some time been using FT methods to overcome some of the difficulties involved in making high resolution studies of the upper atmosphere. For limb absorption measurements from balloon platforms, the critical requirement is the need to record the interferogram in short enough time to prevent distortion of the spectrum by the changing line-of-sight air mass. Here, the time available is typically 100 seconds, and current instruments can record the entire near and mid-IR spectrum at about 0.01 cm-1 resolution within this interval. To increase the altitude and latitude coverage of such measurements, however, by making the observations from space platforms, the process must be speeded up by two orders of magnitude. The Atmospheric Trace Molecules Spectroscopy (ATMOS) experiment, which uses a shuttle-borne Connes-type interferometer covering the two to sixteen micron range, is described. The measurements will provide the first opportunity to obtain simultaneously the vertical profiles of all of the infrared active trace constituents with relative concentrations as low as 10-12, throughout the stratosphere and mesosphere. In addition to problems in the instrument design, the experiment presents major challenges in data management.