4 November 1981 Intravenous Angiocardiography Using Digital Image Processing: Experience With Axial Projections In Normal Pigs And In Pigs With Experimentally Generated Left-To-Right Shunts
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Abstract
Computerized digitization and processing of roentgen video images recorded at a rate of 50 per second was tested in intravenous angiocardiography in normal pigs weighing 15 to 20 kg. Roentgen video images were recorded in the 4-chamber view obtained by 30-35 degrees caudocranial angulation of the x-ray tube and 50-60 degrees LAO obliquity in the pig. Significant contrast enhancement was obtained through ECG-gated background subtraction and rescaling after integration of multiple background as well as contrast images. Occasionally, histogram equalization was used to further enhance contrast. To study temporal changes in cardiac motion, time parameter extraction or functional imaging was applied as well. The left and right heart were well visualized after intravenous injection of 1/3-1 cc. 76% Urografin per kg. bodyweight. Special purpose processing like subtraction of the end systolic phase from the end diastolic in the left and right ventricles as well as subtraction of the right ventricular phase from the left ventricular phase was also performed. If the left ventricular end systolic phase was subtracted from the end diastolic, most of the left atrium was also subtracted whereby the left ventricle was seen without continuity or superimposition of the left atrium. Experimentally generated ventricular and atrial septal defects as well as patent ductus arteriosus could be detected using the described technique. The results of the animal experiments became the basis for subsequent applications in children with congenital heart disease.
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Hugo G. Bogren, Hugo G. Bogren, Joachim H. Bursch, Joachim H. Bursch, Rudiger Brennecke, Rudiger Brennecke, Paul H. Heintzen, Paul H. Heintzen, } "Intravenous Angiocardiography Using Digital Image Processing: Experience With Axial Projections In Normal Pigs And In Pigs With Experimentally Generated Left-To-Right Shunts", Proc. SPIE 0314, Digital Radiography, (4 November 1981); doi: 10.1117/12.933060; https://doi.org/10.1117/12.933060
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