3 August 1984 On-Line Archiving And Enhancement Of Diagnostic Electron Microscope Images In Medicine
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Abstract
The development of computer tomography (CT) in radiography has stimulated recent interest in picture archiving and communication systems (PACS) in medicine. Electron microscopy and histopathol-ogy also use interpretation of images in diagnosis. We have implemented a prototype system for on-line digitization of tissue images as a part of PACS based on DEC PDP 8, VAX 11/730 and PDP 11/35 processors. The front end processor was directly connected to a JEOL 100B scanning transmission electron microscope (STEM). Because image digitization results in a loss of information that is present in photography, various methods of image enhancement and filtering were necessary and helpful. Data compression by discrete cosine transform (DCT) retained satisfac-tory image quality at 0.5 - 1.0 bits/pixel. It is also stressed that future PACS in medi-cine must incorporate images of diagnostic histo-pathology and electron microscopy.
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T. Okagaki, R. Hsing, K. H. Tzou, M. H. Jones, B. A. Clark, T. Pan, J. M. Ferro, "On-Line Archiving And Enhancement Of Diagnostic Electron Microscope Images In Medicine", Proc. SPIE 0515, Medical Images and Icons, (3 August 1984); doi: 10.1117/12.964748; https://doi.org/10.1117/12.964748
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