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25 November 1985 Retinal Blood-Flow Visualization And Measurement By Means Of Laser Speckle Photography
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We present results of an investigation into the visualization and measurement of retinal blood-flow distribution by means of single-exposure laser-speckle fundus photography. The technique relies on the speckle effect produced when laser light is scattered at a diffusing structure and on the fact that the speckle will be averaged out to some extent when the structure concerned is moving and/or decorrelating. We discuss two alternative techniques used to process the specklegrams obtained from the retina. The first technique uses an analog optical spatial filtering procedure to enhance the resulting variations in speckle contrast. Although first results have shown the basic usefulness of this technique it suffers from fundamental disadvantages. In the second technique we digitize the specklegram and use digital image processing techniques (1) to convert to contrast variations in the fundus photography into colour variations and (2) to obtain the blood flow of the vessels with a reasonable low statistical error.
© (1985) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
A. F. Fercher and M. Peukert "Retinal Blood-Flow Visualization And Measurement By Means Of Laser Speckle Photography", Proc. SPIE 0556, Intl Conf on Speckle, (25 November 1985);

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