The major aims in tissue characterization are the differentiation between normal, benign and malignant (primary/metastasic) tissues. Usually the information of standard spin echo images as well as the MR parameters T1, T2 and spin density are used for clinical diagnosis. Pattern recognition methods are applied to improve the specificity of MRI. The variety of all these parameters requires the selection of the parameters containing the relevant diagnostic information. Therefore images with optimum contrast to a given diagnostic task are generated.