Stimulation Of Wound Healing By Lasers

Richard F. Lyons; R.Patrick Abergel; Thomas s. Lam; Rodney A. White; Richard M. Dwyer; Jouni Uitto

doi:10.1117/12.956347

5 August 1986 Stimulation Of Wound Healing By Lasers

Richard F. Lyons, R.Patrick Abergel, Thomas s. Lam, Rodney A. White, Richard M. Dwyer, Jouni Uitto

Proceedings Volume 0605, Optical and Laser Technology in Medicine; (1986) https://doi.org/10.1117/12.956347
Event: O-E/LASE'86 Symposium, 1986, Los Angeles, CA, United States

Abstract

Clinical observations have suggested that low energy lasers might stimulate wound healing. To understand the mechanism of the biostimulation, we have previously examined the effects of low energy lasers on collagen production by human skin fibroblasts and reported an increase of collagen synthesis in vitro (J. Am. Acad. Derm. 11:1142-1150, 1980. To examine the effects of low energy lasers in vivo, hairless mice were experimentally wounded, sutured and subjected to laser irradiation by He-Ne laser with a power output of 1.56 mW, and an energy fluence of 1.22 J/cm². Experimental wounds were subjected to laser treatment every other day, for a total duration of 2 months; control wounds remained untreated. Specimens from the wounds were then examined for histology, tensile strength and total collagen content. Results demonstrated a considerable improvement of the tensile strength of the laser-irradiated wounds at 1 and 2 weeks. Furthermore, the total collagen content was significantly increased at 2 months when compared to control wounds. These results suggest a beneficial effect of He-Ne laser on wound healing in vivo.

Citation Download Citation

Richard F. Lyons, R.Patrick Abergel, Thomas s. Lam, Rodney A. White, Richard M. Dwyer, and Jouni Uitto "Stimulation Of Wound Healing By Lasers", Proc. SPIE 0605, Optical and Laser Technology in Medicine, (5 August 1986); https://doi.org/10.1117/12.956347

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available