The Nova laser is a high-power, pulsed, neodymium-glass system used for inertial confinement fusion and X-ray laser research at the Lawrence Livermore National Laboratory. The control system aligns the ten 250-m-long beams by closing approximately 300 automatic loops. TV alignment sensor images are image processed to extract laser beam and reference information. Two-dimensional techniques that have been applied to process these images include correlation, convolution, gradient, centroid, Hough transform, and histogram equalization. These techniques combine to form algorithms that are relatively insensitive to image Intensity. This paper describes practical image processing methods and reliability measures developed for automatic alignment.