10 March 1987 In Vivo Measurements On Human Lens Using Quasielastic Light Scattering
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Proceedings Volume 0712, Lasers in Medicine; (1987) https://doi.org/10.1117/12.937336
Event: Cambridge Symposium-Fiber/LASE '86, 1986, Cambridge, MA, United States
Quasi-elastic light scattering is a useful method to determine the size distribution of sub-micron particles in fluids. We have applied this technique to measure in vivo changes in the association of human lens protein constituents that occur with aging and cataractogenesis. The autocorrelation function of the scattered light has been analyzed by a two component exponential where each component is characterized by an intensity and decay rate. Each pair of parameters is associated with one of two major protein compo-nents in the lens. Our results seem to be consistent with the model of progressive aggregation of the lens proteins as detected in vitro by other biochemical methods.
© (1987) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Peter C. Magnante, Leo T. Chylack, George B. Benedek, and Teodosio Libondi "In Vivo Measurements On Human Lens Using Quasielastic Light Scattering", Proc. SPIE 0712, Lasers in Medicine, (10 March 1987); doi: 10.1117/12.937336; https://doi.org/10.1117/12.937336

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