The photosensitizing properties of hematoporphyrin derivative (HPD) have been investigated using egg phosphatidylcholine liposomes and resealed bovine erythrocyte membranes (ghosts) as model membranes. The results demonstrate that incorporated HPD photosensitizes lipid peroxidation in liposome and ghost membranes and protein cross-linking in ghosts via the Type 2, singlet oxygen mechanism.
Leonard I. Grossweiner,
"Photosensitization Of Model Membranes By HPD: Implications For Photodynamic Therapy", Proc. SPIE 0712, Lasers in Medicine, (10 March 1987); doi: 10.1117/12.937332; https://doi.org/10.1117/12.937332