Design Of A Fibre Optic Probe For The In-Vivo Determination Of Photosensitizing Drugs

P. R. King; J. B. Dawson; I. Driver; D. J. Ellis; J. W. Feather

doi:10.1117/12.941108

14 October 1987 Design Of A Fibre Optic Probe For The In-Vivo Determination Of Photosensitizing Drugs

P. R. King, J. B. Dawson, I. Driver, D. J. Ellis, J. W. Feather

Proceedings Volume 0798, Fiber Optic Sensors II; (1987) https://doi.org/10.1117/12.941108
Event: Fourth International Symposium on Optical and Optoelectronic Applied Sciences and Engineering, 1987, The Hague, Netherlands

Abstract

The design of a fibre optic probe for the fluorescence detection of photosensitizing drugs used in photochemotherapy is described. The probe is designed to use Raman scattering of the exciting radiation by water molecules to correct for the variable optical properties of in vivo sample volumes. In vitro tests of the probe in scattering and non-scattering media are reported, and the feasibility of obtaining quantitative data in vivo is discussed.

Citation Download Citation

P. R. King, J. B. Dawson, I. Driver, D. J. Ellis, and J. W. Feather "Design Of A Fibre Optic Probe For The In-Vivo Determination Of Photosensitizing Drugs", Proc. SPIE 0798, Fiber Optic Sensors II, (14 October 1987); https://doi.org/10.1117/12.941108

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