Absorbance-Based Affinity Glucose Sensor

Sohrab Mansouri; Cheryl Jones; Roy Martin; Ron Heil

doi:10.1117/12.945255

21 June 1988 Absorbance-Based Affinity Glucose Sensor

Sohrab Mansouri, Cheryl Jones, Roy Martin, Ron Heil

Proceedings Volume 0906, Optical Fibers in Medicine III; (1988) https://doi.org/10.1117/12.945255
Event: 1988 Los Angeles Symposium: O-E/LASE '88, 1988, Los Angeles, CA, United States

Abstract

A fluorescence-based optical affinity glucose sensor which offers the advantage of equilibrium reactions has been developed. However, our efforts to miniaturize its optical components is hampered by unavailability of a suitable solid state emitter. An absorbance-based sensor is investigated to overcome the miniaturization difficulty of the optical system. A suitable dye is selected and tagged to the dextran. A small and portable optical detector using a photodiode and a red LED is fabricated. Our preliminary in vitro, results indicates the feasibility of this approach as an ambulatory glucose sensor.

Citation Download Citation

Sohrab Mansouri, Cheryl Jones, Roy Martin, and Ron Heil "Absorbance-Based Affinity Glucose Sensor", Proc. SPIE 0906, Optical Fibers in Medicine III, (21 June 1988); https://doi.org/10.1117/12.945255

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