21 June 1988 Argon Ion Laser Induced Tissue Fluorescence: Clinical Spectroscopic Studies
Author Affiliations +
Proceedings Volume 0906, Optical Fibers in Medicine III; (1988) https://doi.org/10.1117/12.945300
Event: 1988 Los Angeles Symposium: O-E/LASE '88, 1988, Los Angeles, CA, United States
In conjunction with our project in laser angiosurgery, our group has demonstrated that laser-induced auto-fluorescence can be a reliable means of distinguishing normal artery from atherosclerotic plaque. Recently a number of groups have become interested in this technique as a means of directing ablation of arterial obstructions in vivo. However, until now, diagnostic spectroscopy has been conducted almost solely on excised cadaveric tissues. As a result, questions still remain about 1) the validity of correlating cadaveric tissue fluorescence spectra with those collected in vivo, and 2) the ability to collect reliable florescence spectra from a subject as dynamic as a living patient.
© (1988) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
R. Cothren, R. Cothren, T. Kolubayev, T. Kolubayev, B. T. Kjellstrom, B. T. Kjellstrom, R. Richards-Kortum, R. Richards-Kortum, B. Healy, B. Healy, N. Ratliff, N. Ratliff, G. Engelmann, G. Engelmann, F. Loop, F. Loop, J. R. Kramer, J. R. Kramer, C. Kittrell, C. Kittrell, } "Argon Ion Laser Induced Tissue Fluorescence: Clinical Spectroscopic Studies", Proc. SPIE 0906, Optical Fibers in Medicine III, (21 June 1988); doi: 10.1117/12.945300; https://doi.org/10.1117/12.945300

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