21 June 1988 Optical Transduction Of Chemoreceptive Events: Towards A Fiber-Optic Biosensor
Author Affiliations +
Proceedings Volume 0906, Optical Fibers in Medicine III; (1988) https://doi.org/10.1117/12.945254
Event: 1988 Los Angeles Symposium: O-E/LASE '88, 1988, Los Angeles, CA, United States
Phosphatidyl choline-cholesterol and stearic acid monolayers and multilayers were deposited onto borosilicate glass, quartz and crystalline silicon surfaces by transfer from the air-water interface of a Langmuir-Blodgett trough. Contact angle, ellipsometric, X-ray photoelectron and fluorescence measurements provided characterization of phospholipid monolayers on hydrated or alkylated silicate surfaces. A fluorescent lipid film supported on a quartz optical fiber demonstrated the feasibility of preparation of an evanescent-wave based intrinsic optrode. Further development of intrinsic biosensors based on lipid membrane structures is described in terms of optical conduction of lipid multilayer wave guides, and new membrane-soluble fluorescence probes such as trans-4-dimethylamino-4'-(1-oxobutyl)stilbene.
© (1988) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Ulrich J. Krull, R. Stephen Brown, A. Safarzadeh-Amiri, "Optical Transduction Of Chemoreceptive Events: Towards A Fiber-Optic Biosensor", Proc. SPIE 0906, Optical Fibers in Medicine III, (21 June 1988); doi: 10.1117/12.945254; https://doi.org/10.1117/12.945254

Back to Top