Pulsed Laser Ablation Of Calcified Plaque

M. R. Prince; R. R. Anderson; T. F. Deutsch; G. M. LaMuraglia

doi:10.1117/12.945296

21 June 1988 Pulsed Laser Ablation Of Calcified Plaque

M. R. Prince, R. R. Anderson, T. F. Deutsch, G. M. LaMuraglia

Proceedings Volume 0906, Optical Fibers in Medicine III; (1988) https://doi.org/10.1117/12.945296
Event: 1988 Los Angeles Symposium: O-E/LASE '88, 1988, Los Angeles, CA, United States

Abstract

Laser ablation of calcific plaque in human arteries has been demonstrated with visible radiation at intensities (107 W/cm2) that are readily transmitted by flexible (320 μm diameter) quartz optical fibers. The ablative mechanism involves formation of a plasma with mechanical fragmentation of the plaque by stress waves rather than simply thermal vaporization. By appropriate selection of laser pulse duration (<50 μsec), wavelength and exposure, the laser pulse can ablate the calcified plaque but will not ablate normal artery. These optimized laser parameters may enhance the safety and efficacy of laser endarterectomy.

Citation Download Citation

M. R. Prince, R. R. Anderson, T. F. Deutsch, and G. M. LaMuraglia "Pulsed Laser Ablation Of Calcified Plaque", Proc. SPIE 0906, Optical Fibers in Medicine III, (21 June 1988); https://doi.org/10.1117/12.945296

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