Immunofluorescence Detection For Fiber Optics Chemical And Biological Sensors

T Vo -Dinh; B J Tromberg; M J Sepaniak; G D Griffin; K R Ambrose; R M Santella

doi:10.1117/12.945444

27 April 1988 Immunofluorescence Detection For Fiber Optics Chemical And Biological Sensors

T Vo -Dinh, B J Tromberg, M J Sepaniak, G D Griffin, K R Ambrose, R M Santella

Proceedings Volume 0910, Fluorescence Detection II; (1988) https://doi.org/10.1117/12.945444
Event: 1988 Los Angeles Symposium: O-E/LASE '88, 1988, Los Angeles, CA, United States

Abstract

This paper presents the development and applidation of immunofluorescence spectroscopy in fiberoptics-based chemical and biological sensors. Focus is on a fluoroimmuno-sensor (FIS), which combines the excellent specificity of the antigen-antibody reaction and the high sensitivity of laser excitation and the versatility of fiberoptics technology. The FIS can detect 40 attomoles (10-18 mole) of benzo(a)pyrene tetrol, a DNA-adduct product of the carcinogen benzo(a)pyrene.

Citation Download Citation

T Vo -Dinh, B J Tromberg, M J Sepaniak, G D Griffin, K R Ambrose, and R M Santella "Immunofluorescence Detection For Fiber Optics Chemical And Biological Sensors", Proc. SPIE 0910, Fluorescence Detection II, (27 April 1988); https://doi.org/10.1117/12.945444

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