A Digital Optically Multiplexed Charge Coupled Device (CCD) Based Deoxyribonucleic Acid (DNA) Sequence Reader

Eric R. Craine; Brian L. Craine; John R. Engel; Neil T. Wemple; Ron Hilliard

doi:10.1117/12.968675

27 June 1988 A Digital Optically Multiplexed Charge Coupled Device (CCD) Based Deoxyribonucleic Acid (DNA) Sequence Reader

Eric R. Craine, Brian L. Craine, John R. Engel, Neil T. Wemple, Ron Hilliard

Author Affiliations +

Proceedings Volume 0914, Medical Imaging II; (1988) https://doi.org/10.1117/12.968675
Event: Medical Imaging II, 1988, Newport Beach, CA, United States

Abstract

We have developed a unique prototype solid state digital imaging system for use in the analysis of one dimensional deoxyribonucleic acid (DNA) sequencing gels. The system can be used to digitize, interpret and store DNA sequence information directly from an autoradiogram. The system consists of a two dimensional charge coupled device (CCD) imager, a multiplexing optical front end for reformatting of the gel image, a microcomputer host and a software package for reconstruction of the gel image and analysis of the DNA sequence.

Citation Download Citation

Eric R. Craine, Brian L. Craine, John R. Engel, Neil T. Wemple, and Ron Hilliard "A Digital Optically Multiplexed Charge Coupled Device (CCD) Based Deoxyribonucleic Acid (DNA) Sequence Reader", Proc. SPIE 0914, Medical Imaging II, (27 June 1988); https://doi.org/10.1117/12.968675

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