In this paper is studying multi-phase fluid flow simulation in a blending tank, which involve air and water. It aims to use a model of the turbulence of the fluid, addicted to set different options for each fluid turbulence. It used for simulation the equations and tools from program ANSYS 13.0. The system is composed of a tank, a pipe of air injection, four baffles, a rotor, and a vertical shaft passing through the vessel. Data entry: the rotation frequency of the rotor on axis Ox (89 rotations/min(rpm)), the speed of the air which is injected into the container (5 m/s ), diameter pipe at entry (0.0248 m).The study assumptions are: a) the temperature of the water and the air remain constant (25 °C) and that the air is incompressible, with a density equal to that at 25 0 C and 1 Pa; b) the bubbles have 3 mm diameter. The mixture requires two domains: a domain for rotor and stationary tank area. Both areas contain water as a continuous phase and air as the dispersion phase. The fields will shape buoyancy, turbulence and the forces of the fluid. In the paper are presented the details of flow analysis for: dispersed fluid in the impeller region of mixing device and of continuous fluid in the same region, with corresponding parameters, after this for tank and the boundary conditions for each studied assumptions. Flow simulation in blending tank help to optimize the shape of tank and reducing the hydraulic losses due to fouling the solid borders.