Translator Disclaimer
Paper
9 December 2016 Seed mediated one-pot growth of versatile heterogeneous upconversion nanocrystals for multimodal bioimaging
Author Affiliations +
Proceedings Volume 10013, SPIE BioPhotonics Australasia; 1001315 (2016) https://doi.org/10.1117/12.2245172
Event: SPIE BioPhotonics Australasia, 2016, Adelaide, Australia
Abstract
The rapid development of a variety of molecular contrast agents makes the multimodality bioimaging highly attractive towards higher resolution, more sensitive, informative diagnosis. The key lies in the development of facile material synthesis that allows the integration of multiple contrast agents, ideally in a way that each of the components should be logically assembled to maximize their performances. Here, we report the one-pot programmable growth of multifunctional heterogeneous nanocrystal with tunable size, shape, composition, and properties. We demonstrated a facile one-pot hot-injection method to enable the highly selectively controlled growth of different sodium lanthanide fluoride nanomaterials in either longitudinal or transversal directions with atomic scale precision. This technique allows the upconversion luminescence signal, MRI signal and x-ray signal logically integrated and optimized within one single versatile nanoplatform for multimode bioimaging. These findings suggest that the facile strategy developed here have the promising to get the desired heterogeneous nanocrystals as an all-in-one contrast agent for integrated and self-correlative multimodal bioimaging.
© (2016) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Shihui Wen, Du Li, Deming Liu, Xiaoxue Xu, Yi Du, David R. G. Mitchell, Bingyang Shi, Xiangyang Shi, and Dayong Jin "Seed mediated one-pot growth of versatile heterogeneous upconversion nanocrystals for multimodal bioimaging", Proc. SPIE 10013, SPIE BioPhotonics Australasia, 1001315 (9 December 2016); https://doi.org/10.1117/12.2245172
PROCEEDINGS
7 PAGES


SHARE
Advertisement
Advertisement
RELATED CONTENT

Tailoring lanthanide nanocrystals for nanomedicine
Proceedings of SPIE (February 22 2013)
Delivery of gene-expressing fragments using quantum dot
Proceedings of SPIE (March 03 2009)
Use of upconverting fluorescent nanoparticles for bioimaging
Proceedings of SPIE (February 23 2012)
Luminescent nanoparticles for molecular medicine
Proceedings of SPIE (July 13 2007)

Back to Top