24 November 2016 Fluorometric biosniffer (biochemical gas sensor) for breath acetone as a volatile indicator of lipid metabolism
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Abstract
A fluorometric acetone biosniffer (biochemical gas sensor) for assessment of lipid metabolism utilizing reverse reaction of secondary alcohol dehydrogenase was constructed and evaluated. The biosniffer showed highly sensitivity and selectivity for continuous monitoring of gaseous acetone. The measurement of breath acetone concentration during fasting and aerobic exercise were also investigated. The acetone biosniffer provides a novel analytical tool for noninvasive evaluation of human lipid metabolism and it is also expected to use for the clinical and physiological applications such as monitoring the progression of diabetes.
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Kohji Mitsubayashi, Kohji Mitsubayashi, Po-Jen Chien, Po-Jen Chien, Ming Ye, Ming Ye, Takuma Suzuki, Takuma Suzuki, Koji Toma, Koji Toma, Takahiro Arakawa, Takahiro Arakawa, } "Fluorometric biosniffer (biochemical gas sensor) for breath acetone as a volatile indicator of lipid metabolism", Proc. SPIE 10013, SPIE BioPhotonics Australasia, 100131T (24 November 2016); doi: 10.1117/12.2244660; https://doi.org/10.1117/12.2244660
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