With the advantages of high resolution, large field of view and compacted size, optoelectronic imaging sensors are widely used in many fields, such as robot’s navigation, industrial measurement and remote sensing. Many researchers pay more attention to improve the comprehensive performances of imaging sensors, including large field of view (FOV), high resolution, compact size and high imaging efficiency, etc. One challenge is the tradeoff between high resolution and large field of view simultaneously considering compacted size. In this paper, we propose an optoelectronic imaging system combining the lenses of short focal length and long focal length based on dual CMOS to simulate the characters of human eyes which observe object within large FOV in high resolution. We design and optimize the two lens, the lens of short focal length is used to search object in a wide field and the long one is responsible for high resolution imaging of the target area. Based on a micro-CMOS imaging sensor with low voltage differential transmission technology-MIPI (Mobile Industry Processor Interface), we design the corresponding circuits to realize collecting optical information with high speed. The advantage of the interface is to help decreasing power consumption, improving transmission efficiency and achieving compacted size of imaging sensor. Meanwhile, we carried out simulations and experiments to testify the optoelectronic imaging system. The results show that the proposed method is helpful to improve the comprehensive performances of optoelectronic imaging sensors.