31 October 2016 Structured light imaging system for structural and optical characterization of 3D tissue-simulating phantoms
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There is a pressing need for a phantom standard to calibrate medical optical devices. However, 3D printing of tissue-simulating phantom standard is challenged by lacking of appropriate methods to characterize and reproduce surface topography and optical properties accurately. We have developed a structured light imaging system to characterize surface topography and optical properties (absorption coefficient and reduced scattering coefficient) of 3D tissue-simulating phantoms. The system consisted of a hyperspectral light source, a digital light projector (DLP), a CMOS camera, two polarizers, a rotational stage, a translation stage, a motion controller, and a personal computer. Tissue-simulating phantoms with different structural and optical properties were characterized by the proposed imaging system and validated by a standard integrating sphere system. The experimental results showed that the proposed system was able to achieve pixel-level optical properties with a percentage error of less than 11% for absorption coefficient and less than 7% for reduced scattering coefficient for phantoms without surface curvature. In the meanwhile, 3D topographic profile of the phantom can be effectively reconstructed with an accuracy of less than 1% deviation error. Our study demonstrated that the proposed structured light imaging system has the potential to characterize structural profile and optical properties of 3D tissue-simulating phantoms.
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Songde Liu, Songde Liu, Zach Smith, Zach Smith, Ronald X. Xu, Ronald X. Xu, } "Structured light imaging system for structural and optical characterization of 3D tissue-simulating phantoms", Proc. SPIE 10024, Optics in Health Care and Biomedical Optics VII, 100240P (31 October 2016); doi: 10.1117/12.2247773; https://doi.org/10.1117/12.2247773

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