Light emitting fabric for photodynamic treatment of actinic keratosis

E. Thecua; C. Vicentini; A-S. Vignion; F. Lecomte; P. Deleporte; L. Mortier; R.-M. Szeimies; S. Mordon

doi:10.1117/12.2252201

6 February 2017 Light emitting fabric for photodynamic treatment of actinic keratosis

E. Thecua, C. Vicentini, A-S. Vignion, F. Lecomte, P. Deleporte, L. Mortier, R.-M. Szeimies, S. Mordon

Proceedings Volume 10037, Photonics in Dermatology and Plastic Surgery; 100370L (2017) https://doi.org/10.1117/12.2252201
Event: SPIE BiOS, 2017, San Francisco, California, United States

Abstract

The integration of optical fibers into flexible textile structures, by using knitting or weaving processes can allow the development of flexible light sources. The paper aims to present a new technology: Light Emitting Fabrics (LEF), which can be used for example for PDT of Actinic Keratosis in Dermatology. The predetermined macro-bending of optical fibers, led to a homogeneous side emission of light over the entire surface of the fabric. Tests showed that additional curvatures when applying the LEF on non-planar surfaces had no impact on light delivery and proved that LEF can adapt to the human morphology. The ability of the LEF, coupled with a 635nm LASER source, to deliver a homogeneous light to lesions is currently assessed in a clinical trial for the treatment of AK of the scalp by PDT. The low irradiance and progressive activation of the photosensitizer ensure a pain reduction, compared to discomfort levels experienced by patients during a conventional PDT session.

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Citation Download Citation

E. Thecua, C. Vicentini, A-S. Vignion, F. Lecomte, P. Deleporte, L. Mortier, R.-M. Szeimies, and S. Mordon "Light emitting fabric for photodynamic treatment of actinic keratosis", Proc. SPIE 10037, Photonics in Dermatology and Plastic Surgery, 100370L (6 February 2017); https://doi.org/10.1117/12.2252201

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