6 February 2017 Light emitting fabric for photodynamic treatment of actinic keratosis
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Abstract
The integration of optical fibers into flexible textile structures, by using knitting or weaving processes can allow the development of flexible light sources. The paper aims to present a new technology: Light Emitting Fabrics (LEF), which can be used for example for PDT of Actinic Keratosis in Dermatology. The predetermined macro-bending of optical fibers, led to a homogeneous side emission of light over the entire surface of the fabric. Tests showed that additional curvatures when applying the LEF on non-planar surfaces had no impact on light delivery and proved that LEF can adapt to the human morphology. The ability of the LEF, coupled with a 635nm LASER source, to deliver a homogeneous light to lesions is currently assessed in a clinical trial for the treatment of AK of the scalp by PDT. The low irradiance and progressive activation of the photosensitizer ensure a pain reduction, compared to discomfort levels experienced by patients during a conventional PDT session.
Conference Presentation
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E. Thecua, C. Vicentini, A-S. Vignion, F. Lecomte, P. Deleporte, L. Mortier, R.-M. Szeimies, S. Mordon, "Light emitting fabric for photodynamic treatment of actinic keratosis", Proc. SPIE 10037, Photonics in Dermatology and Plastic Surgery, 100370L (6 February 2017); doi: 10.1117/12.2252201; https://doi.org/10.1117/12.2252201
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