20 February 2017 The study of laser pulse width on efficiency of Ho:YAG laser lithotripsy
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Abstract
When treating ureteral calculi, retropulsion can be reduced by using a longer pulse width without compromising fragmentation efficiency (from the studies by David S. Finley et al. and Hyun Wook Kang et al.). In this study, a lab build Ho:YAG laser was used as the laser pulse source, with pulse energy from 0.2J up to 3.0 J, and electrical pump pulse width from 150 us up to 1000 us. The fiber used in the investigation is a 365 μm core diameter fiber, SureFlexTM, Model S-LLF365. Plaster of Paris calculus phantoms were ablated at different energy levels (0.2, 0.5, 1, 2, 3J) and with different number of pulses (1, 3, 10) using different electrical pump pulse width (333, 667, 1000 μs). The dynamics of the recoil action of a calculus phantom was monitored using a high-speed camera with frame rate up to 1 million frame per second (Photron Fastcam SA5); and the laser-induced craters were evaluated with a 3-D digital microscope (Keyence VHX-900F). A design of experiment software (DesignExpert-10, Minneapolis, MN, USA) is used in this study for the best fit of surface response on volume of dusting and retropulsion amplitude. The numerical formulas for the response surfaces of dusting speed and retropulsion amplitude are generated. More detailed investigation on the optimal conditions for dusting of other kinds of stone samples and the fiber size effect will be conducted as a future study.
Conference Presentation
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Jian J. Zhang, Jian J. Zhang, Jonathan Rutherford, Jonathan Rutherford, Metasebya Solomon, Metasebya Solomon, Brian Cheng, Brian Cheng, Jason R. Xuan, Jason R. Xuan, Jason Gong, Jason Gong, Honggang Yu, Honggang Yu, Michael Xia, Michael Xia, Xirong Yang, Xirong Yang, Thomas Hasenberg, Thomas Hasenberg, Sean Curran, Sean Curran, } "The study of laser pulse width on efficiency of Ho:YAG laser lithotripsy", Proc. SPIE 10038, Therapeutics and Diagnostics in Urology: Lasers, Robotics, Minimally Invasive, and Advanced Biomedical Devices, 100380H (20 February 2017); doi: 10.1117/12.2250665; https://doi.org/10.1117/12.2250665
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