21 February 2017 Towards noninvasive drug distribution in tissues: coherent Raman microspectroscopy of chiral molecules
Author Affiliations +
Abstract
Many biologically active molecules are chiral. Many drugs, which are currently in use, are supplied as an equimolar mixture of enantiomers. Although they have the same chemical structure, i.e. are not distinguishable by conventional Raman spectroscopy, most isomers of chiral drugs exhibit marked differences in biological activities such as pharmacology, toxicology, pharmacokinetics, metabolism, etc. In this report we introduced a new spectroscopic tool to extend nonlinear Raman spectroscopy to chiral substances.
Conference Presentation
© (2017) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Georgi I. Petrov, Georgi I. Petrov, Vladislav V. Yakovlev, Vladislav V. Yakovlev, } "Towards noninvasive drug distribution in tissues: coherent Raman microspectroscopy of chiral molecules", Proc. SPIE 10046, Visualizing and Quantifying Drug Distribution in Tissue, 1004604 (21 February 2017); doi: 10.1117/12.2252944; https://doi.org/10.1117/12.2252944
PROCEEDINGS
4 PAGES + PRESENTATION

SHARE
Back to Top