Laser acupuncture is an effective photochemical and nonthermal stimulation of traditional acupuncture points with lowintensity
laser irradiation, which is advantageous in painless, sterile, and safe compared to traditional acupuncture. Laser
diode (LD) provides single wavelength and relatively-higher power light for phototherapy. The quantitative effect of
illumination parameters of LD in use of laser acupuncture is crucial for practical operation of laser acupuncture.
However, this issue is not fully demonstrated, especially since experimental methodologies with animals or human are
pretty hard to address to this issue. For example, in order to protect viability of cells and tissue, and get better therapeutic
effect, it’s necessary to control the output power varied at 5mW~10mW range, while the optimized power is still not
clear. This study aimed to quantitatively optimize the laser output power, wavelength, and irradiation direction with
highly realistic modeling of light transport in acupunctured tissue. A Monte Carlo Simulation software for 3D vowelized
media and the highest-precision human anatomical model Visible Chinese Human (VCH) were employed. Our 3D
simulation results showed that longer wavelength/higher illumination power, larger absorption in laser acupuncture; the
vertical direction emission of the acupuncture laser results in higher amount of light absorption in both the acupunctured
voxel of tissue and muscle layer. Our 3D light distribution of laser acupuncture within VCH tissue model is potential to
be used in optimization and real time guidance in clinical manipulation of laser acupuncture.