20 February 2017 Using stereotactic brain atlases for small rodents and nonhuman primates for optrode array customization
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Proceedings Volume 10052, Optogenetics and Optical Manipulation; 1005204 (2017) https://doi.org/10.1117/12.2251601
Event: SPIE BiOS, 2017, San Francisco, California, United States
Abstract
As the optogenetic field expands its need to target with high specificity only grows more crucial. This work will show a method for customizing soda-lime glass optrode arrays so that fine structures within the brains of small rodents and nonhuman primates can be optically interrogated below the outer cortical layer. An 8 × 6 array is customized for optrode length (400 μm ), optrode width (75 μm ), optrode pitch (400 μm ), backplane thickness (500 μm ), and overall form factor (3.45 mm × 2.65 mm ). The 400 μm long optrode is capable of illuminating the cortical Layer IV of rhesus macaque ( Macaca Fascicularis ) and the motor cortex of small mice ( Mus Musculus ).
Conference Presentation
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Ronald W. Boutte, Ronald W. Boutte, Sam Merlin, Sam Merlin, Brandon Griffiths, Brandon Griffiths, Trent Parry, Trent Parry, Steve Blair, Steve Blair, } "Using stereotactic brain atlases for small rodents and nonhuman primates for optrode array customization", Proc. SPIE 10052, Optogenetics and Optical Manipulation, 1005204 (20 February 2017); doi: 10.1117/12.2251601; https://doi.org/10.1117/12.2251601
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