17 February 2017 Gold nanoparticles evaluation using functional optical coherence tomography
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Abstract
The main object of this research was to assess the ability to characterize the gold nanoparticles using optical modalities like optical coherence tomography. Since the nanoparticles, especially gold one, have been very attractive for medical diagnosis and treatment the amount of research activities have been growing rapidly. The nanoparticles designed for different applications like contrast agents or drugs delivery change the optical features of tissue in different way. Therefore, the expanded analysis of scattering optical signal may lead to obtain much more useful information about the tissues health and the treatment efficiency. The noninvasive measurements of the concentration and distribution of the nanoparticles, as well as their size in the media have been taken under consideration. For this purpose the polarization sensitive optical coherence tomography system with spectroscopic analysis (PS-SOCT) has been designed and used. In this contribution we are going to present the PS-SOCT measurement data obtained for the gold nanoparticles. The measurements have been taken for the liquid (gold nanoparticles in water) samples changing the particles concentrations in time.
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Marcin R. Strąkowski, Marcin R. Strąkowski, Maciej Głowacki, Maciej Głowacki, Aleksandra Kamińska, Aleksandra Kamińska, Mirosław Sawczak, Mirosław Sawczak, } "Gold nanoparticles evaluation using functional optical coherence tomography", Proc. SPIE 10053, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXI, 1005336 (17 February 2017); doi: 10.1117/12.2254912; https://doi.org/10.1117/12.2254912
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