Development of an antimicrobial blended white LED system containing pulsed 405nm LEDs for decontamination applications

Jonathan B. Gillespie; Michelle Maclean; Mark P. Wilson; Martin J. Given; Scott J. MacGregor

doi:10.1117/12.2250539

14 March 2017 Development of an antimicrobial blended white LED system containing pulsed 405nm LEDs for decontamination applications

Jonathan B. Gillespie, Michelle Maclean, Mark P. Wilson, Martin J. Given, Scott J. MacGregor

Author Affiliations +

Proceedings Volume 10056, Design and Quality for Biomedical Technologies X; 100560Y (2017) https://doi.org/10.1117/12.2250539
Event: SPIE BiOS, 2017, San Francisco, California, United States

Abstract

This study details the design, build and testing of a prototype antimicrobial blended white light unit containing pulsed red, yellow, green and 405nm LEDs. With a push for alternative methods of disinfection, optical methods have become a topic of interest. Ultra-violet (UV) light is widely known for its antimicrobial properties however; 405nm light has demonstrated significant antimicrobial properties against many common hospital acquired pathogens. In this study, a pulsed, blended, white-light prototype with a high content of 405 nm antimicrobial light, was designed, built and tested. Antimicrobial efficacy testing of the prototype was conducted using Staphylococcus aureus and Pseudomonas. aeruginosa, two bacteria which are common causes of hospital acquired infections. These were exposure to 3 different light outputs from the prototype and the surviving bacteria enumerated. Results showed that the mixed light output provided a much better CRI and light output under which to work. Also, the light output containing 405 nm light provided an antimicrobial effect, with decontamination of 10³ CFUml^-1 populations of both bacterial species. The other light content (red, yellow, green) had no beneficial or adverse effects on the antimicrobial properties of the 405nm light. The results suggest that with further development, it could be possible to produce an antimicrobial blended white light containing pulsed 405nm light that could supplement or even replace standard white lighting in certain environments.

Citation Download Citation

Jonathan B. Gillespie, Michelle Maclean, Mark P. Wilson, Martin J. Given, and Scott J. MacGregor "Development of an antimicrobial blended white LED system containing pulsed 405nm LEDs for decontamination applications", Proc. SPIE 10056, Design and Quality for Biomedical Technologies X, 100560Y (14 March 2017); https://doi.org/10.1117/12.2250539

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available