20 April 2017 Towards a clinical implementation of μOCT instrument for in vivo imaging of human airways
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Abstract
High resolution micro-optical coherence tomography (µOCT) technology has been demonstrated to be useful for imaging respiratory epithelial functional microanatomy relevant to the study of pulmonary diseases such as cystic fibrosis and COPD. We previously reported the use of a benchtop μOCT imaging technology to image several relevant respiratory epithelial functional microanatomy at 40 fps and at lateral and axial resolutions of 2 and 1.3μm, respectively. We now present the development of a portable μOCT imaging system with comparable optical and imaging performance, which enables the μOCT technology to be translated to the clinic for in vivo imaging of human airways.
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Hui Min Leung, Hui Min Leung, Dongyao Cui, Dongyao Cui, Timothy N. Ford, Timothy N. Ford, Daryl Hyun, Daryl Hyun, Jing Dong, Jing Dong, Biwei Yin, Biwei Yin, Susan E. Birket, Susan E. Birket, George M. Solomon, George M. Solomon, Linbo Liu, Linbo Liu, Steven M. Rowe, Steven M. Rowe, Guillermo J. Tearney, Guillermo J. Tearney, } "Towards a clinical implementation of μOCT instrument for in vivo imaging of human airways", Proc. SPIE 10056, Design and Quality for Biomedical Technologies X, 1005614 (20 April 2017); doi: 10.1117/12.2253423; https://doi.org/10.1117/12.2253423
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