28 February 2017 Ultraviolet spectroscopic breath analysis using hollow-optical fiber as gas cell
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Abstract
For breath analysis on ultraviolet absorption spectroscopy, an analysis system using a hollow optical fiber as gas cell is developed. The hollow optical fiber functions as a long path and extremely small volume gas cell. Firstly, the measurement sensitivity of the system is evaluated by using NO gas as a gas sample. The result shows that NO gas with 50 ppb concentration is measured by using a system with a laser-driven, high intensity light source and a 3-meter long, aluminum-coated hollow optical fiber. Then an absorption spectrum of breath sample is measured in the wavelength region of around 200-300 nm and from the spectrum, it is found that the main absorbing components in breath were H2O, isoprene, and O3 converted from O2 by radiation of ultraviolet light. Then the concentration of isoprene in breath is estimated by using multiple linear regression analysis.
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T. Iwata, T. Iwata, T. Katagiri, T. Katagiri, Y. Matsuura, Y. Matsuura, } "Ultraviolet spectroscopic breath analysis using hollow-optical fiber as gas cell", Proc. SPIE 10058, Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVII, 1005806 (28 February 2017); doi: 10.1117/12.2249662; https://doi.org/10.1117/12.2249662
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