17 February 2017 Diffuse speckle contrast analysis with novel fiber-lens detection
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Abstract
To date, various blood flow measurement systems have been presented. Recently we demonstrated multi-channel diffuse speckle contrast analysis (DSCA) to monitor in-vivo relative blood flow in deep tissues noninvasively. It has a limitation in a long-term use due to camera contamination. Here, we present a novel fiber-lens combined DSCA which can solve it. Also it has been applied to cerebral blood flow monitoring of rats during middle cerebral artery occlusion surgery. As a result, the system showed relative changes of the flow during the arterial perfusion periods. It secures novel applications of the DSCA in in-vivo blood flow measurement.
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Chaebeom Yeo, Chaebeom Yeo, Cheol Song, Cheol Song, } "Diffuse speckle contrast analysis with novel fiber-lens detection", Proc. SPIE 10059, Optical Tomography and Spectroscopy of Tissue XII, 1005904 (17 February 2017); doi: 10.1117/12.2255085; https://doi.org/10.1117/12.2255085
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