18 February 2017 Breast cancer detection using Ktrans MRI imaging to guide near infrared spectroscopy tomography
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Abstract
The parametric image of Volume Transfer Coefficient (Ktrans) in MRI has been used to guide image reconstruction of Near-Infrared Spectral Tomography (NIRST). The image reconstruction used direct regularization, in which no segmentation has been involved. A total of 24 patients were involved in this study and the reconstructed results show that the tumor total hemoglobin (HbT) contrast could be used to differentiate the malignant from the benign cases (p-value= 0.018). The addition of the MRI information allows more accurate and definitive HbT values from the NIRST.
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Jinchao Feng, Jinchao Feng, Shudong Jiang, Shudong Jiang, Junqing Xu, Junqing Xu, Yan Zhao, Yan Zhao, Jiang Gui, Jiang Gui, Brian W. Pogue, Brian W. Pogue, Keith D. Paulsen, Keith D. Paulsen, } "Breast cancer detection using Ktrans MRI imaging to guide near infrared spectroscopy tomography", Proc. SPIE 10059, Optical Tomography and Spectroscopy of Tissue XII, 100590O (18 February 2017); doi: 10.1117/12.2250649; https://doi.org/10.1117/12.2250649
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