27 March 2017 Feasibility study of spatial frequency domain imaging using a handheld miniaturized projector and rigid endoscope
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Abstract
Initial feasibility of a spatial frequency domain imaging system was studied consisting of a hand held miniaturized projector and a rigid endoscope. Three wavelengths and two spatial frequencies were used for imaging. The system was calibrated using tissue mimicking phantoms. In vivo imaging was performed on five live mouse tumor models, and the absorption, scattering, hemoglobin oxygen saturation was measured. The initial promising results indicate that the spatial frequency domain imaging can a very useful tool for quantitative wide field tissue evaluation during minimally invasive image guided surgery.
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Sreyankar Nandy, Mohsen Erfanzadeh, Feifei Zhou, Quing Zhu, "Feasibility study of spatial frequency domain imaging using a handheld miniaturized projector and rigid endoscope", Proc. SPIE 10059, Optical Tomography and Spectroscopy of Tissue XII, 100591S (27 March 2017); doi: 10.1117/12.2253221; https://doi.org/10.1117/12.2253221
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