17 February 2017 Single snapshot determination of absorption coefficient by multi-frequency MTF characterization in spatial frequency domain
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Abstract
We present a novel approach for single snapshot determination of absorption coefficient based on multi-frequency modulation transfer function (MTF) characterization from measurement in spatial frequency domain. The adopted Fourier transform domain analysis enables simultaneous extraction of information at multiple applied frequencies and excellent reduction of noise. Simulations were conducted for respectively verifying the feasibility of the MTF based approach and the performance of single snapshot determination of absorption coefficient using multi-frequency measurements. Phantom experiments without reference measurement demonstrated the high accuracy of absolute absorption coefficient determination with a maximum reconstruction error of 0.002 mm-1.
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Weiting Chen, Weiting Chen, Tongxin Li, Tongxin Li, Caixia Qi, Caixia Qi, Panpan Yan, Panpan Yan, Feng Gao, Feng Gao, Huijuan Zhao, Huijuan Zhao, } "Single snapshot determination of absorption coefficient by multi-frequency MTF characterization in spatial frequency domain", Proc. SPIE 10059, Optical Tomography and Spectroscopy of Tissue XII, 100591T (17 February 2017); doi: 10.1117/12.2253448; https://doi.org/10.1117/12.2253448
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