17 February 2017 Quantification of hemoglobin and its derivatives in oral cancer diagnosis by diffuse reflectance spectroscopy
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Abstract
Cancer is one of the most common threat to human beings and it increases at an alarming level around the globe. In recent years, due to the advancements in opto-electronic technology, various optical spectroscopy techniques have emerged to assess the photophysicochemical and morphological conditions of normal and malignant tissues in micro as well as in macroscopic scale. In this regard, diffuse reflectance spectroscopy is considered to be the simplest, cost effective and rapid technique in diagnosis of cancerous tissues. In the present study, the hemoglobin concentration in normal and cancerous oral tissues was quantified and subsequent statistical analysis has been carried out to verify the diagnostic potentiality of the technique.
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Udayakumar Kaniyappan, Udayakumar Kaniyappan, Einstein Gnanatheepam, Einstein Gnanatheepam, Prakasarao Aruna, Prakasarao Aruna, Koteeswaran Dornadula, Koteeswaran Dornadula, Singaravelu Ganesan, Singaravelu Ganesan, } "Quantification of hemoglobin and its derivatives in oral cancer diagnosis by diffuse reflectance spectroscopy", Proc. SPIE 10060, Optical Biopsy XV: Toward Real-Time Spectroscopic Imaging and Diagnosis, 100601F (17 February 2017); doi: 10.1117/12.2255874; https://doi.org/10.1117/12.2255874
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