15 February 2017 Short pulse laser induced thermo-elastic deformation imaging
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Abstract
Absorption of nanosecond laser pulses induces rapid thermo-elastic deformation in tissue, i.e. a sub-micrometer scale displacement happens within a couple of microseconds. In this study, we initially investigate the depth-resolved deformation using a 1.5 MHz phase-sensitive optical coherence tomography (OCT) system. Functional images can be reconstructed based on the detected deformation, which enables a new imaging modality called thermo-elastic deformation imaging (TDI). Our results show that the associated displacement is related to the optical absorption of the short laser pulses. The TDI images can provide tissue type information in addition to the conventional OCT images.
Conference Presentation
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Tianshi Wang, Tianshi Wang, Tom Pfeiffer, Tom Pfeiffer, Min Wu, Min Wu, Wolfgang Wieser, Wolfgang Wieser, Wolfgang Draxinger, Wolfgang Draxinger, Antonius F. W. van der Steen, Antonius F. W. van der Steen, Robert Huber, Robert Huber, Gijs van Soest, Gijs van Soest, } "Short pulse laser induced thermo-elastic deformation imaging", Proc. SPIE 10062, Optical Interactions with Tissue and Cells XXVIII, 100620C (15 February 2017); doi: 10.1117/12.2251502; https://doi.org/10.1117/12.2251502
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