23 March 2017 Identification and removal of reflection artifacts in minimally invasive photoacoustic imaging for accurate visualization of brachytherapy seeds
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Abstract
Reflection artifacts caused by the high signal from the optical fiber/ needle tip reflecting off the seed is an important problem in minimally invasive photoacoustic imaging of brachytherapy seeds. The presence of these artifacts confounds the interpretation of images and reduces contrast. We apply a new method called PAFUSion (Photoacoustic-guided focused ultrasound) to identify and reduce reflection artifacts generated in interstitial illumination imaging of brachytherapy seeds. We present the system comprising of a US imager and linear array, with illumination provided via a cutting needle. Non-radioactive brachytherapy seeds are implanted in a tissue mimicking phantom and ex vivo porcine tissue. The PAFUSion-corrected imaging results successfully demonstrate that our approach can identify and strongly reduce reflection artifacts in the context of photoacoustic needle. The phantom result also shows that multi-spectral photoacoustics can separate signals between the seeds and other optical absorbers.
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Mithun Kuniyil Ajith Singh, Mithun Kuniyil Ajith Singh, Vinay Parameshwarappa, Vinay Parameshwarappa, Ellen Hendriksen, Ellen Hendriksen, Wiendelt Steenbergen, Wiendelt Steenbergen, Srirang Manohar, Srirang Manohar, } "Identification and removal of reflection artifacts in minimally invasive photoacoustic imaging for accurate visualization of brachytherapy seeds", Proc. SPIE 10064, Photons Plus Ultrasound: Imaging and Sensing 2017, 100640G (23 March 2017); doi: 10.1117/12.2252561; https://doi.org/10.1117/12.2252561
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