23 March 2017 Imaging small animal whole-body dynamics by single-impulse panoramic photoacoustic computed tomography
Author Affiliations +
Imaging of small animals, especially rodents provides physiological, pathological, and phenotypical insights into the most relevant milieu—an intact, living system. Currently, non-optical small-animal wholebody imaging approaches lack either spatiotemporal resolution or functional contrasts, whereas pure optical imaging suffers from either shallow penetration (up to ~1 mm) or a poor resolution-to-depth ratio (~1/3). Here, we present a standalone system that breaks all the above limitations. Our system features high spatiotemporal resolution and deep penetration, and can capture anatomical and functional contrasts. We imaged mouse wholebody dynamics in real time with clear sub-organ anatomical and functional details.
Conference Presentation
© (2017) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Lei Li, Lei Li, Liren Zhu, Liren Zhu, Cheng Ma, Cheng Ma, Li Lin, Li Lin, Junjie Yao, Junjie Yao, Lidai Wang, Lidai Wang, Konstantin Maslov, Konstantin Maslov, Ruiying Zhang, Ruiying Zhang, Wanyi Chen, Wanyi Chen, Junhui Shi, Junhui Shi, Lihong V. Wang, Lihong V. Wang, } "Imaging small animal whole-body dynamics by single-impulse panoramic photoacoustic computed tomography", Proc. SPIE 10064, Photons Plus Ultrasound: Imaging and Sensing 2017, 100640M (23 March 2017); doi: 10.1117/12.2251593; https://doi.org/10.1117/12.2251593

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