3 March 2017 Compression-tracking photoacoustic perfusion and microvascular pressure measurements
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Abstract
We propose a method to measure blood pressure of small vessels non-invasively and in-vivo: by combining PA imaging with compression US. Using this method, we have shown pressure-lumen area tracking, as well as estimation of the internal vessel pressure, located 2 mm deep in tissue. Additionally, reperfusion can be tracked by measuring the total PA signal within a region of interest (ROI) after compression has been released. The ROI is updated using cross-correlation based displacement tracking1. The change in subcutaneous perfusion rates can be seen when the temperature of the hand of a human subject drops below the normal.
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Min Choi, Roger Zemp, "Compression-tracking photoacoustic perfusion and microvascular pressure measurements", Proc. SPIE 10064, Photons Plus Ultrasound: Imaging and Sensing 2017, 100643R (3 March 2017); doi: 10.1117/12.2253287; https://doi.org/10.1117/12.2253287
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