16 February 2017 Usage of CT data in biomechanical research
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Object of study: The investigation is focused on development of personalized medicine. The determination of mechanical properties of bone tissues based on in vivo data was considered. Methods: CT, MRI, natural experiments on versatile test machine Instron 5944, numerical experiments using Python programs. Results: The medical diagnostics methods, which allows determination of mechanical properties of bone tissues based on in vivo data. The series of experiments to define the values of mechanical parameters of bone tissues. For one and the same sample, computed tomography (CT), magnetic resonance imaging (MRI), ultrasonic investigations and mechanical experiments on single-column test machine Instron 5944 were carried out. The computer program for comparison of CT and MRI images was created. The grayscale values in the same points of the samples were determined on both CT and MRI images. The Haunsfield grayscale values were used to determine rigidity (Young module) and tensile strength of the samples. The obtained data was compared to natural experiments results for verification.
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Roman A. Safonov, Roman A. Safonov, Anastasiya A. Golyadkina, Anastasiya A. Golyadkina, Irina V. Kirillova, Irina V. Kirillova, Leonid Y. Kossovich, Leonid Y. Kossovich, } "Usage of CT data in biomechanical research", Proc. SPIE 10068, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XV, 100681O (16 February 2017); doi: 10.1117/12.2250881; https://doi.org/10.1117/12.2250881

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