21 February 2017 In situ monitoring of collagen fibers in human skin using a photonic-crystal-fiber-coupled, hand-held, second-harmonic-generation microscope
Author Affiliations +
Abstract
Second-harmonic-generation (SHG) microscopy is a powerful tool for in situ monitoring of collagen fibers in human skin. However, its practical use is still limited in the dermatological field due to the bulky and complicated setup. In this paper, we constructed a photonic-crystal-fiber-coupled, hand-held SHG microscope for in situ monitoring of collagen fibers in human skin. Fiber delivery of femtosecond pulse light was achieved by a large-mode-area photonic-crystal-fiber whereas the compact SHG microscopy setup was enclosed into a lens tube system. The combination of PCF with the lens tube system largely enhances the flexibility of measurement sites in the human skin.
© (2017) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
K. Atsuta, K. Atsuta, Y. Ogura, Y. Ogura, E. Hase, E. Hase, T. Minamikawa, T. Minamikawa, T. Yasui, T. Yasui, } "In situ monitoring of collagen fibers in human skin using a photonic-crystal-fiber-coupled, hand-held, second-harmonic-generation microscope", Proc. SPIE 10069, Multiphoton Microscopy in the Biomedical Sciences XVII, 100692B (21 February 2017); doi: 10.1117/12.2251321; https://doi.org/10.1117/12.2251321
PROCEEDINGS
6 PAGES


SHARE
RELATED CONTENT


Back to Top