17 February 2017 Portable SERS sensor for malachite green and other small dye molecules
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Sensitive detection of specific chemicals on site can be extremely powerful in many fields. Owing to its molecular fingerprinting capability, surface-enhanced Raman scattering has been one of the technological contenders. In this paper, we describe the novel use of DNA topological nanostructure on nanoporous gold nanoparticle (NPG-NP) array chip for chemical sensing. NPG-NP features large surface area and high-density plasmonic field enhancement known as “hotspots”. Hence, NPG-NP array chip has found many applications in nanoplasmonic sensor development. This technique can provide novel label-free molecular sensing capability and enables high sensitivity and specificity detection using a portable Raman spectrometer.
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Suyan Qiu, Suyan Qiu, Fusheng Zhao, Fusheng Zhao, Jingting Li, Jingting Li, Wei-Chuan Shih, Wei-Chuan Shih, } "Portable SERS sensor for malachite green and other small dye molecules", Proc. SPIE 10072, Optical Diagnostics and Sensing XVII: Toward Point-of-Care Diagnostics, 1007202 (17 February 2017); doi: 10.1117/12.2252559; https://doi.org/10.1117/12.2252559

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