17 February 2017 Picosecond laser ablation of polyamide electrospun nanofibers
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Abstract
Electrospun nanofibers mats have a great potential in tissue engineering and regenerative medicine. Their high porosity and enormous volume to surface ratio stimulate the growth and adhesion of mammalian cells and serve as a stable support structure. These suitable properties can be further optimized by structuring of the nanofibers. Ultrashort pulsed lasers can be used for modifying of the electrospun nanofibers without significant heat exposure. It seems also possible to generate very fine cuts from the fiber mats.

In this study, polyamide electrospun nanofibers samples were processed with picosecond UV-laser irradiation (λ = 355 nm, τ = 15 ps). The samples were processed in dry, wet and immersed condition. To optimize cutting and structuring of nanofiber tissue flakes, the influence of different laser parameters on line widths, edge quality, heat-affected zone (HAZ) and the contamination of the fibers by ablated particles (debris) were examined. One additional aim was the minimization of the flake size. It was possible to generate nanofiber flakes in the sub-millimeter range. The quality of the nanofiber flakes could be improved by ablation near the ablation threshold of the material. For cutting under wet conditions shrinking of the flakes has to be taken into account.
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Marco Götze, Marco Götze, Olaf Krimig, Olaf Krimig, Tobias Kürbitz, Tobias Kürbitz, Sven Henning, Sven Henning, Andreas Heilmann, Andreas Heilmann, Georg Hillrichs, Georg Hillrichs, } "Picosecond laser ablation of polyamide electrospun nanofibers", Proc. SPIE 10094, Frontiers in Ultrafast Optics: Biomedical, Scientific, and Industrial Applications XVII, 100940R (17 February 2017); doi: 10.1117/12.2252312; https://doi.org/10.1117/12.2252312
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