27 January 2017 Detection of prostate specific antigen using silicon photonic crystal nanocavity resonator
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Abstract
In this work, we investigated photonic crystal (PhC) based double nanocavity resonator biosensor. The sensor performance has confirmed by both sucrose and prostate specific antigen (PSA, a protein biomarker associated with prostate cancer). The device sensitivity and quality factor in sucrose solution are 1571 nm/RIU (Refractive Index Unit) and 2×105 respectively. By using special antigen-antibody reaction, we successfully detected PSA concentration as low as 0.5 ng/mL.
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Amrita Kumar Sana, Amrita Kumar Sana, Yoshiteru Amemiya, Yoshiteru Amemiya, Takeshi Ikeda, Takeshi Ikeda, Akio Kuroda, Akio Kuroda, Shin Yokoyama, Shin Yokoyama, } "Detection of prostate specific antigen using silicon photonic crystal nanocavity resonator", Proc. SPIE 10111, Quantum Sensing and Nano Electronics and Photonics XIV, 1011138 (27 January 2017); doi: 10.1117/12.2251604; https://doi.org/10.1117/12.2251604
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